What next for both teams?Getty ImagesVery different domestic aspirations for these two teams the rest of the way.Manchester United, as Ruben Amorim alluded to, are all in on the Europa League so their Premier League games will be little more than warm-ups.

They host Wolves at Old Trafford on Sunday, when I suspect the stadium might have just about stopped shaking!As for Lyon, they still have Champions League qualification to play for.

They are also in action on Sunday, with a trip to face relegation-threatened Saint-Etienne.Tolisso: ‘You have to move on with your life’More from Tolisso after sobering night for him and his team-mates.“We’re going to have to get back to work quickly.

You have to forget.

It’s hard to say, but there you go, it’s done,” he said.“It’s done and you’ve got to move on with your life.

Even if we’ve been hit tonight, we’re going to get up again on Sunday.“When you’re winning 4-2 with 10 minutes to go and you’re already in the semi-finals, being eliminated, not even having made it to the penalty shoot-out.

Of course it makes you feel even more regret.”When are the semi-finals?Getty ImagesI think we all need a week off to rest after these three evenings of European football chaos.No Champions League or Europa League matches next week, but then we’re back to do it all over again the week after.So a fortnight to wait for the first legs of the semi-finals on Thursday, May 1.

The second legs will be played a week later on Thursday, May 8.More from Tolisso: We have to learn from thisAnd Tolisso tried to make sense of what happened in stoppage time to deny his side the win.“I was off the pitch, so I was in the stands,” he concluded.

“I can tell you about my personal situation when I celebrated.

“When we put in the fourth, I was super happy, I thought we were going to win.

But nothing’s over.

They managed to score that third goal.

After that, they followed it up with the fourth and fifth in quick succession.

We’ll be able to learn from that and move on.“They gave it their all.

Honestly, we deserve better.

For me, we were better than that team and I’m sure that if we stay 11 against 11, we’ll go through and qualify.

Now things are done.

We can’t go back to the past.

But it hurts.

“Frankly, I can’t hide the fact that it really hurts my head.

Now, we’re still professionals.

We’re going to have to digest all that and really concentrate on Sunday, because we’ve got this Champions League place to seek.”Tolisso: ‘It really hurts’Getty ImagesCorentin Tolisso went through the full range of emotions this evening with a goal that Lyon back into the game and then the late red card.“Complicated, disappointing,” he said.

“We missed our first half completely, two goals but we said things to each other at half-time.

We came back with better intentions and managed to get back on level terms.

“We had a really good second half, and then the game turned on its head when I was sent off, unfortunately.

Deserved or not, I don’t know.

I haven’t seen the footage so I couldn’t tell you.

For me, it’s a bit light because from what I feel, he comes into my path, he touches me and I can’t avoid it.

“But after that, the boys didn’t give up, they managed to score those two goals and that’s what’s really very frustrating.

We were winning 4-2 with 10 minutes to go, you concede those three goals, it really hurts.”An Old Trafford night fans could never see againGetty ImagesI’m curious on a night like tonight whether any fans feel differently about Manchester United knocking this stadium down?Just about sums it up!Couldn’t have said it better ourselves.The Europa League semi-finals are set!UEFASo, after all of this evening’s chaos, we now know which four teams will be battling it out for a place in the final in Bilbao on May 21.Tottenham will face Norwegians minnows Bodo/Glimt, who have done a fantastic job to make it this far.United, meanwhile, face Athletic Club, the team based in the city where the final will be played.A Tottenham vs Manchester United final anyone?Your reactions: ‘We’re s***, but we’re s*** with aura’Getty ImagesFans have been piling into The Athletic’s discussion tab at the top of the page and clickable here.Hans P questioned: Are we not entertained???? 😆😆😆😆Barry W posted: We’re s***, but we’re s*** with aura.And Kevin F concluded: That was for that kid who had tears in their eyes!!Get involved yourself, or email us at: live@theathletic.com with your thoughts!Yoro: ‘I don’t understand what happened’Leny Yoro turned in another big performance for United this evening and he spoke to TNT Sports after the match.“Honestly, I don’t understand what happened! That was crazy,” he said.

“The fans were crazy, they really helped us today.”Asked what he was feeling when Lyon went 4-2 up in extra time, the 19-year-old said: “A lot of things, it was difficult.

But, even at 4-2, when you hear the fans, you know you can do it.

When we scored the penalty, I was sure.“That was too crazy to not win this game.”Amorim: Everyone believes we can win itGetty ImagesAs Amorim mentioned, full focus on the Europa League from here and he was asked in that interview if he believes his men can lift the trophy.“Yes, you can see it in the stadium.

Everybody believes that it is possible,” he said.

“We need to have a bit of luck with injuries to reach that with some players.”He had already discussed how vital it is to have injured players returning to full fitness at the right time.“It’s really important because, when you are here, you can feel that playing Premier League and European games is really hard.

If you don’t have a full squad, it’s almost impossible,” added Amorim.“Mason Mount brings us experience, Luke Shaw was meant to play 30 minutes tops but we had a problem with Nouss (Mazraoui) at half-time, Vic (Lindelof) has a personal problem, he had to leave.

So all this stuff happened during this game but, in the end, it was a good day.”GO FURTHERRuben Amorim: Old Trafford ‘the best sound I’ve ever heard’ after dramatic Harry Maguire winnerA moment that can change everything, says AmorimMore from Ruben Amorim to TNT Sports.“It’s one of those moments that can change a lot of things,” he said.

“Sometimes we just look at the tactical or physical aspect, but this kind of moment can change a lot in the players’ minds.“We have to be really focused on Europa League, we have to take a risk sometimes with the kids in the Premier League and we have to be tough on that and the fans have to understand that we want to focus on Europa League.”Amorim explains decision to throw Maguire and Mainoo up topRasmus Hojlund was, once again, really poor for United and it turned to be a masterstroke from Amorim to swap the Dane out for the surprise strike force of Maguire and Mainoo.“We tried to put Harry Maguire (up front) because he’s the only guy that can score a goal with his head,” he told TNT Sports.

“And then Kobbie Mainoo has a lack of pace in this moment because he had that injury and he stopped for a while.

But he’s really good in small spaces and then he has the ability to score that kind of goal.“We tried, sometimes it works and today was a good day.”Those poor Lyon fansGetty ImagesDespair for the away fans, who did their team proud.Amorim: It’s never over at Old TraffordGetty ImagesRuben Amorim wore a grin as he spoke to TNT Sports after the match.“It was hard.

I was watching again the ‘(19)99 (Champions League final) commentary to have some inspiration for this moment.

It was a great night,” he said.“The team was tired, you could feel it during the game and then 4-2 with one more player and you think it’s over.

But here, it’s never over.

Everything is possible.

“You feel the environment.

After Bruno’s penalty, you felt that the game could change.”Leny Yoro speaking now…Manchester United defender Leny Yoro is speaking to TNT Sports.We’ll bring you his quotes, and those of manager Ruben Amorim, shortly.A word for LyonGetty ImagesTonight was really tough on Lyon.The French side weren’t perfect but worked really hard, didn’t give up the fight when 2-0 down, coming back to deservedly draw level.They were then cut down to 10 men after Corentin Tolisso’s harsh red card.Despite that, they somehow battled to two goals ahead.In the end, United’s extra man made the difference at the end.

And United got a leg up in the previous round with some dodgy penalties against Real Sociedad too!The king of comebacks?Harry Maguire, centre forward.

Who would have thought it?Manchester United were dead and buried, two goals down in this tie and crashing out of the Europa League in calamitous fashion having been 2-0 up on the night, 4-2 on aggregate, thanks to goals from Manuel Ugarte and Diogo Dalot.And then the most unlikely collection of things happened to send United to a semi-final against Athletic Club on May 1 and May 8.

Talk about the king of comebacks.Everyone catch your breath…